Are there nonstop flights from Melbourne (MEL) to Johannesburg (JNB)?

No. The fastest connection is via Perth, about 13h 58m of total flying time.

What is the fastest connection from Melbourne (MEL) to Johannesburg (JNB)?

via Perth ≈ 13h 58m, via Sydney ≈ 14h 48m, via Singapore ≈ 18h 17m (estimated flying time, excluding layovers).

from 35,000 ANA miles, from 45,000 JAL miles (economy, one way, based on the published award charts).

Melbourne Airport (MEL) to O.R. Tambo International Airport (JNB)・10,319 km

No nonstop flights. The fastest connection is via Perth (PER), about 13h 58m of flying time (layover not included).

With milesANA 35,000 miles+ (via SIN)JAL 45,000 miles+ (via PER)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

9 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.