Are there nonstop flights from Medina (MED) to Istanbul (SAW)?

Yes. Pegasus Airlines, AJet fly this route. Flight time is about 2h 55m.

What is the fastest connection from Medina (MED) to Istanbul (SAW)?

via Amman ≈ 3h 25m, via Beirut ≈ 3h 26m, via Damascus ≈ 3h 27m (estimated flying time, excluding layovers).

from 23,000 JAL miles (economy, one way, based on the published award charts).

Prince Mohammad Bin Abdulaziz Airport (MED) to Istanbul Sabiha Gökçen International Airport (SAW)・2,058 km

Nonstop flights available (2 airlines). Flight time about 2h 55m. Nonstop return flights also operate.

With milesJAL 23,000 miles+ (via DOH)Economy, one way, estimate. Tap a connection for miles by cabin.

23 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.