Are there nonstop flights from Mendoza (MDZ) to Santa Cruz (VVI)?

No. The fastest connection is via Santiago, about 3h 29m of total flying time.

What is the fastest connection from Mendoza (MDZ) to Santa Cruz (VVI)?

via Santiago ≈ 3h 29m, via Buenos Aires ≈ 4h 28m (estimated flying time, excluding layovers).

Governor Francisco Gabrielli International Airport (MDZ) to Viru Viru International Airport (VVI)・1,781 km

No nonstop flights. The fastest connection is via Santiago (SCL), about 3h 29m of flying time (layover not included).

None.

2 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.