Are there nonstop flights from Harrisburg (MDT) to New York (LGA)?

No. The fastest connection is via Washington, about 1h 37m of total flying time.

What is the fastest connection from Harrisburg (MDT) to New York (LGA)?

via Washington ≈ 1h 37m, via Boston ≈ 1h 59m (estimated flying time, excluding layovers).

Harrisburg International Airport (MDT) to LaGuardia Airport (LGA)・253 km

No nonstop flights. The fastest connection is via Washington (IAD), about 1h 37m of flying time (layover not included).

None.

2 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.