Are there nonstop flights from Medellín (MDE) to Istanbul (IST)?

No. The fastest connection is via Madrid, about 13h 38m of total flying time.

What is the fastest connection from Medellín (MDE) to Istanbul (IST)?

via Madrid ≈ 13h 38m, via Maiquetía ≈ 13h 39m, via Bogota ≈ 13h 52m (estimated flying time, excluding layovers).

from 35,000 ANA miles (economy, one way, based on the published award charts).

Jose Maria Córdova International Airport (MDE) to İstanbul Airport (IST)・10,722 km

No nonstop flights. The fastest connection is via Madrid (MAD), about 13h 38m of flying time (layover not included).

With milesANA 35,000 miles+ (via MAD)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

13 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.