Are there nonstop flights from Medellín (MDE) to Panamá City (BLB)?

Yes. Wingo fly this route. Flight time is about 1h 9m.

What is the fastest connection from Medellín (MDE) to Panamá City (BLB)?

via Cartagena ≈ 2h 8m, via Bogota ≈ 2h 9m, via Cali ≈ 2h 11m (estimated flying time, excluding layovers).

Jose Maria Córdova International Airport (MDE) to Panamá Pacífico International Airport (BLB)・553 km

Nonstop flights available (1 airline). Flight time about 1h 9m. Nonstop return flights also operate.

4 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.