Are there nonstop flights from Orlando (MCO) to San Antonio (SAT)?

Yes. Southwest Airlines, Frontier Airlines fly this route. Flight time is about 2h 28m.

What is the fastest connection from Orlando (MCO) to San Antonio (SAT)?

via Houston ≈ 2h 58m, via Houston ≈ 2h 59m, via New Orleans ≈ 2h 59m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Orlando International Airport (MCO) to San Antonio International Airport (SAT)・1,672 km

Nonstop flights available (2 airlines). Flight time about 2h 28m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via IAH)JAL 15,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

30 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.