Are there nonstop flights from Orlando (MCO) to Kailua-Kona (KOA)?

No. The fastest connection is via San Diego, about 9h 54m of total flying time.

What is the fastest connection from Orlando (MCO) to Kailua-Kona (KOA)?

via San Diego ≈ 9h 54m, via Dallas-Fort Worth ≈ 9h 54m, via Phoenix ≈ 9h 54m (estimated flying time, excluding layovers).

from 23,500 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Orlando International Airport (MCO) to Ellison Onizuka Kona International Airport at Keāhole (KOA)・7,533 km

No nonstop flights. The fastest connection is via San Diego (SAN), about 9h 54m of flying time (layover not included).

With milesANA 23,500 miles+ (via LAX)JAL 37,000 miles+ (via SAN)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

13 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.