Are there nonstop flights from Madrid (MAD) to Manchester (MAN)?

Yes. Ryanair, easyJet, Iberia Express fly this route. Flight time is about 2h 11m.

What is the fastest connection from Madrid (MAD) to Manchester (MAN)?

via Bilbao ≈ 2h 41m, via Santander ≈ 2h 41m, via Nantes ≈ 2h 42m (estimated flying time, excluding layovers).

from 12,000 JAL miles, from 15,000 ANA miles (economy, one way, based on the published award charts).

Adolfo Suárez Madrid–Barajas Airport (MAD) to Manchester Airport (MAN)・1,433 km

Nonstop flights available (3 airlines). Flight time about 2h 11m. Nonstop return flights also operate.

With milesJAL 12,000 miles+ (via LHR)ANA 15,000 miles+ (via BRU)Economy, one way, estimate. Tap a connection for miles by cabin.

65 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.