Are there nonstop flights from Lyon (LYS) to São Paulo (GRU)?

No. The fastest connection is via Casablanca, about 11h 55m of total flying time.

What is the fastest connection from Lyon (LYS) to São Paulo (GRU)?

via Casablanca ≈ 11h 55m, via Madrid ≈ 11h 55m, via Barcelona ≈ 11h 58m (estimated flying time, excluding layovers).

from 35,000 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Lyon Saint-Exupéry Airport (LYS) to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU)・9,283 km

No nonstop flights. The fastest connection is via Casablanca (CMN), about 11h 55m of flying time (layover not included).

With milesANA 35,000 miles+ (via LIS)JAL 37,000 miles+ (via CMN)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

17 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.