Are there nonstop flights from Luton (LTN) to São Tomé (TMS)?

No. The fastest connection is via Lisbon, about 8h 15m of total flying time.

What is the fastest connection from Luton (LTN) to São Tomé (TMS)?

via Lisbon ≈ 8h 15m (estimated flying time, excluding layovers).

London Luton Airport (LTN) to São Tomé International Airport (TMS)・5,764 km

No nonstop flights. The fastest connection is via Lisbon (LIS), about 8h 15m of flying time (layover not included).

None.

1 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.