Are there nonstop flights from Luton (LTN) to Johannesburg (JNB)?

No. The fastest connection is via Paris, about 11h 44m of total flying time.

What is the fastest connection from Luton (LTN) to Johannesburg (JNB)?

via Paris ≈ 11h 44m, via Zurich ≈ 11h 51m, via Amsterdam ≈ 12h 1m (estimated flying time, excluding layovers).

London Luton Airport (LTN) to O.R. Tambo International Airport (JNB)・9,113 km

No nonstop flights. The fastest connection is via Paris (CDG), about 11h 44m of flying time (layover not included).

None.

6 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.