Are there nonstop flights from Luton (LTN) to São Paulo (GRU)?

No. The fastest connection is via Porto, about 12h 12m of total flying time.

What is the fastest connection from Luton (LTN) to São Paulo (GRU)?

via Porto ≈ 12h 12m, via Lisbon ≈ 12h 13m, via Madrid ≈ 12h 22m (estimated flying time, excluding layovers).

London Luton Airport (LTN) to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU)・9,498 km

No nonstop flights. The fastest connection is via Porto (OPO), about 12h 12m of flying time (layover not included).

None.

11 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.