Are there nonstop flights from La Romana (LRM) to Istanbul (IST)?

No. The fastest connection is via Milan, about 11h 56m of total flying time.

What is the fastest connection from La Romana (LRM) to Istanbul (IST)?

via Milan ≈ 11h 56m, via Rome ≈ 11h 57m, via Madrid ≈ 11h 59m (estimated flying time, excluding layovers).

from 35,000 ANA miles (economy, one way, based on the published award charts).

Casa De Campo International Airport (LRM) to İstanbul Airport (IST)・9,280 km

No nonstop flights. The fastest connection is via Milan (MXP), about 11h 56m of flying time (layover not included).

With milesANA 35,000 miles+ (via YUL)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

11 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.