Are there nonstop flights from London (LCY) to Samos Island (SMI)?

No. The fastest connection is via Thessaloniki, about 4h 4m of total flying time.

What is the fastest connection from London (LCY) to Samos Island (SMI)?

via Thessaloniki ≈ 4h 4m, via Zurich ≈ 4h 4m, via Frankfurt am Main ≈ 4h 5m (estimated flying time, excluding layovers).

London City Airport (LCY) to Samos Airport (SMI)・2,599 km

No nonstop flights. The fastest connection is via Thessaloniki (SKG), about 4h 4m of flying time (layover not included).

None.

4 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.