Are there nonstop flights from London (LCY) to Cairo (CAI)?

No. The fastest connection is via Zurich, about 5h 8m of total flying time.

What is the fastest connection from London (LCY) to Cairo (CAI)?

via Zurich ≈ 5h 8m, via Thessaloniki ≈ 5h 9m, via Frankfurt am Main ≈ 5h 10m (estimated flying time, excluding layovers).

from 30,000 ANA miles (economy, one way, based on the published award charts).

London City Airport (LCY) to Cairo International Airport (CAI)・3,504 km

No nonstop flights. The fastest connection is via Zurich (ZRH), about 5h 8m of flying time (layover not included).

With milesANA 30,000 miles+ (via ZRH)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

10 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.