Are there nonstop flights from Las Vegas (LAS) to São Paulo (GRU)?

No. The fastest connection is via Panama City, about 12h 30m of total flying time.

What is the fastest connection from Las Vegas (LAS) to São Paulo (GRU)?

via Panama City ≈ 12h 30m, via Mexico City ≈ 12h 36m, via Houston ≈ 12h 37m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 45,000 JAL miles (economy, one way, based on the published award charts).

Harry Reid International Airport (LAS) to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU)・9,782 km

No nonstop flights. The fastest connection is via Panama City (PTY), about 12h 30m of flying time (layover not included).

With milesANA 30,000 miles+ (via PTY)JAL 45,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

20 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.