Are there nonstop flights from Kailua-Kona (KOA) to Panama City (PTY)?

No. The fastest connection is via San Diego, about 11h 21m of total flying time.

What is the fastest connection from Kailua-Kona (KOA) to Panama City (PTY)?

via San Diego ≈ 11h 21m, via Los Angeles ≈ 11h 26m, via Las Vegas ≈ 11h 39m (estimated flying time, excluding layovers).

from 35,000 ANA miles (economy, one way, based on the published award charts).

Ellison Onizuka Kona International Airport at Keāhole (KOA) to Tocumen International Airport (PTY)・8,281 km

No nonstop flights. The fastest connection is via San Diego (SAN), about 11h 21m of flying time (layover not included).

With milesANA 35,000 miles+ (via LAX)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

7 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.