Are there nonstop flights from Kailua-Kona (KOA) to Osaka (KIX)?

No. The fastest connection is via Honolulu, about 9h 6m of total flying time.

What is the fastest connection from Kailua-Kona (KOA) to Osaka (KIX)?

via Honolulu ≈ 9h 6m, via Vancouver ≈ 15h 30m, via San Francisco ≈ 15h 43m (estimated flying time, excluding layovers).

from 21,500 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Ellison Onizuka Kona International Airport at Keāhole (KOA) to Kansai International Airport (KIX)・6,870 km

No nonstop flights. The fastest connection is via Honolulu (HNL), about 9h 6m of flying time (layover not included).

With milesANA 21,500 miles+ (via YVR)JAL 37,000 miles+ (via HNL)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

4 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.