Are there nonstop flights from New York (JFK) to Key West (EYW)?

No. The fastest connection is via Orlando, about 3h 18m of total flying time.

What is the fastest connection from New York (JFK) to Key West (EYW)?

via Orlando ≈ 3h 18m, via Miami ≈ 3h 18m, via Raleigh/Durham ≈ 3h 19m (estimated flying time, excluding layovers).

from 15,000 JAL miles (economy, one way, based on the published award charts).

John F. Kennedy International Airport (JFK) to Key West International Airport (EYW)・1,936 km

No nonstop flights. The fastest connection is via Orlando (MCO), about 3h 18m of flying time (layover not included).

With milesJAL 15,000 miles+ (via CLT)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

15 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.