Are there nonstop flights from Jeddah (JED) to Dushanbe (DYU)?

Yes. Somon Air fly this route. Flight time is about 4h 29m.

What is the fastest connection from Jeddah (JED) to Dushanbe (DYU)?

via Kuwait City ≈ 5h, via Mashhad ≈ 5h, via Samarkand ≈ 5h 7m (estimated flying time, excluding layovers).

from 36,000 ANA miles (economy, one way, based on the published award charts).

King Abdulaziz International Airport (JED) to Dushanbe International Airport (DYU)・3,390 km

Nonstop flights available (1 airline). Flight time about 4h 29m. Nonstop return flights also operate.

With milesANA 36,000 miles+ (via IST)Economy, one way, estimate. Tap a connection for miles by cabin.

19 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.