Are there nonstop flights from Jacksonville (JAX) to San Diego (SAN)?

Yes. Breeze Airways fly this route. Flight time is about 4h 27m.

What is the fastest connection from Jacksonville (JAX) to San Diego (SAN)?

via Dallas-Fort Worth ≈ 4h 57m, via Dallas ≈ 4h 57m, via Phoenix ≈ 4h 58m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 23,000 JAL miles (economy, one way, based on the published award charts).

Jacksonville International Airport (JAX) to San Diego International Airport (SAN)・3,355 km

Nonstop flights available (1 airline). Flight time about 4h 27m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via IAH)JAL 23,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

34 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.