Are there nonstop flights from Jacksonville (JAX) to São Paulo (GRU)?

No. The fastest connection is via Miami, about 9h 22m of total flying time.

What is the fastest connection from Jacksonville (JAX) to São Paulo (GRU)?

via Miami ≈ 9h 22m, via Atlanta ≈ 10h 21m, via Washington ≈ 11h 12m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Jacksonville International Airport (JAX) to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU)・7,075 km

No nonstop flights. The fastest connection is via Miami (MIA), about 9h 22m of flying time (layover not included).

With milesANA 30,000 miles+ (via IAD)JAL 37,000 miles+ (via MIA)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

11 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.