Are there nonstop flights from Osaka (ITM) to Ishigaki (ISG)?

No. The fastest connection is via Okinawa (Naha), about 2h 54m of total flying time.

What is the fastest connection from Osaka (ITM) to Ishigaki (ISG)?

via Okinawa (Naha) ≈ 2h 54m, via Fukuoka ≈ 2h 58m, via Tokyo ≈ 3h 46m (estimated flying time, excluding layovers).

from 13,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Osaka Itami International Airport (ITM) to New Ishigaki Airport (ISG)・1,581 km

No nonstop flights. The fastest connection is via Okinawa (Naha) (OKA), about 2h 54m of flying time (layover not included).

With milesANA 13,000 miles+ (via OKA)JAL 15,000 miles+ (via OKA)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

4 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.