Are there nonstop flights from Istanbul (IST) to Minneapolis (MSP)?

No. The fastest connection is via Reykjavík, about 11h 24m of total flying time.

What is the fastest connection from Istanbul (IST) to Minneapolis (MSP)?

via Reykjavík ≈ 11h 24m, via Copenhagen ≈ 11h 25m, via Amsterdam ≈ 11h 26m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

İstanbul Airport (IST) to Minneapolis–Saint Paul International Airport / Wold–Chamberlain Field (MSP)・8,831 km

No nonstop flights. The fastest connection is via Reykjavík (KEF), about 11h 24m of flying time (layover not included).

With milesANA 27,500 miles+ (via YUL)JAL 37,000 miles+ (via CDG)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

28 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.