Are there nonstop flights from St. Mary's (ISC) to Exeter (EXT)?

Yes. Isles of Scilly Skybus fly this route. Flight time is about 46m.

St. Mary's → Exeter

St. Mary's Airport (ISC) to Exeter International Airport (EXT)・224 km

Nonstop flights available (1 airline). Flight time about 46m. Nonstop return flights also operate.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.