Are there nonstop flights from Islamabad (ISB) to Multan (MUX)?

Yes. South Air fly this route. Flight time is about 58m.

Islamabad → Multan

Islamabad International Airport (ISB) to Multan International Airport (MUX)・395 km

Nonstop flights available (1 airline). Flight time about 58m. Nonstop return flights also operate.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.