Are there nonstop flights from Islamabad (ISB) to Moscow (DME)?

No. The fastest connection is via Dushanbe, about 5h 16m of total flying time.

What is the fastest connection from Islamabad (ISB) to Moscow (DME)?

via Dushanbe ≈ 5h 16m, via Tashkent ≈ 5h 19m, via Bishkek ≈ 5h 43m (estimated flying time, excluding layovers).

from 23,000 JAL miles (economy, one way, based on the published award charts).

Islamabad International Airport (ISB) to Domodedovo International Airport (DME)・3,620 km

No nonstop flights. The fastest connection is via Dushanbe (DYU), about 5h 16m of flying time (layover not included).

With milesJAL 23,000 miles+ (via DXB)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

10 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.