Are there nonstop flights from Guayaquil (GYE) to Amsterdam (AMS)?

Yes. KLM fly this route. Flight time is about 12h 4m.

What is the fastest connection from Guayaquil (GYE) to Amsterdam (AMS)?

via Quito ≈ 12h 34m, via Bogota ≈ 12h 34m, via Punta Cana ≈ 12h 36m (estimated flying time, excluding layovers).

from 45,000 JAL miles (economy, one way, based on the published award charts).

José Joaquín de Olmedo International Airport (GYE) to Amsterdam Airport Schiphol (AMS)・9,834 km

Nonstop flights available (1 airline). Flight time about 12h 4m. Nonstop return flights also operate.

With milesJAL 45,000 miles+ (via MAD)Economy, one way, estimate. Tap a connection for miles by cabin.

11 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.