Are there nonstop flights from Guatemala City (GUA) to Quito (UIO)?

No. The fastest connection is via San Salvador, about 3h 29m of total flying time.

What is the fastest connection from Guatemala City (GUA) to Quito (UIO)?

via San Salvador ≈ 3h 29m, via San José ≈ 3h 32m, via Panama City ≈ 3h 49m (estimated flying time, excluding layovers).

from 17,500 ANA miles, from 23,000 JAL miles (economy, one way, based on the published award charts).

La Aurora International Airport (GUA) to Mariscal Sucre International Airport (UIO)・2,114 km

No nonstop flights. The fastest connection is via San Salvador (SAL), about 3h 29m of flying time (layover not included).

With milesANA 17,500 miles+ (via PTY)JAL 23,000 miles+ (via MIA)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

7 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.