Are there nonstop flights from Greenville/Greer/Spartanburg (GSP) to Mexico City (MEX)?

No. The fastest connection is via Atlanta, about 3h 48m of total flying time.

What is the fastest connection from Greenville/Greer/Spartanburg (GSP) to Mexico City (MEX)?

via Atlanta ≈ 3h 48m, via Houston ≈ 4h 2m, via Charlotte ≈ 4h 5m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Greenville-Spartanburg International Airport (GSP) to Mexico City Benito Juárez International Airport (MEX)・2,387 km

No nonstop flights. The fastest connection is via Atlanta (ATL), about 3h 48m of flying time (layover not included).

With milesANA 15,000 miles+ (via IAH)JAL 15,000 miles+ (via CLT)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

13 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.