Are there nonstop flights from Greensboro (GSO) to Chicago (MDW)?

No. The fastest connection is via Charlotte, about 2h 15m of total flying time.

What is the fastest connection from Greensboro (GSO) to Chicago (MDW)?

via Charlotte ≈ 2h 15m, via Detroit ≈ 2h 18m, via Washington ≈ 2h 36m (estimated flying time, excluding layovers).

Piedmont Triad International Airport (GSO) to Chicago Midway International Airport (MDW)・925 km

No nonstop flights. The fastest connection is via Charlotte (CLT), about 2h 15m of flying time (layover not included).

None.

8 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.