Are there nonstop flights from São Paulo (GRU) to Louisville (SDF)?

No. The fastest connection is via Orlando, about 10h 27m of total flying time.

What is the fastest connection from São Paulo (GRU) to Louisville (SDF)?

via Orlando ≈ 10h 27m, via Atlanta ≈ 10h 27m, via Miami ≈ 10h 28m (estimated flying time, excluding layovers).

from 37,000 JAL miles (economy, one way, based on the published award charts).

São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU) to Louisville Muhammad Ali International Airport (SDF)・7,981 km

No nonstop flights. The fastest connection is via Orlando (MCO), about 10h 27m of flying time (layover not included).

With milesJAL 37,000 miles+ (via MIA)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

10 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.