Are there nonstop flights from São Paulo (GRU) to Karachi (KHI)?

No. The fastest connection is via Dubai, about 16h 46m of total flying time.

What is the fastest connection from São Paulo (GRU) to Karachi (KHI)?

via Dubai ≈ 16h 46m, via Addis Ababa ≈ 16h 47m, via Doha ≈ 16h 48m (estimated flying time, excluding layovers).

from 47,000 JAL miles, from 67,500 ANA miles (economy, one way, based on the published award charts).

São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU) to Jinnah International Airport (KHI)・13,351 km

No nonstop flights. The fastest connection is via Dubai (DXB), about 16h 46m of flying time (layover not included).

With milesJAL 47,000 miles+ (via DXB)ANA 67,500 miles+ (via ADD)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

6 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.