Are there nonstop flights from São Paulo (GRU) to Charlotte (CLT)?

No. The fastest connection is via Punta Cana, about 9h 47m of total flying time.

What is the fastest connection from São Paulo (GRU) to Charlotte (CLT)?

via Punta Cana ≈ 9h 47m, via Miami ≈ 9h 58m, via Orlando ≈ 9h 58m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU) to Charlotte Douglas International Airport (CLT)・7,464 km

No nonstop flights. The fastest connection is via Punta Cana (PUJ), about 9h 47m of flying time (layover not included).

With milesANA 30,000 miles+ (via IAD)JAL 37,000 miles+ (via MIA)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

16 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.