Are there nonstop flights from George Town (GCM) to Des Moines (DSM)?

No. The fastest connection is via Atlanta, about 4h 19m of total flying time.

What is the fastest connection from George Town (GCM) to Des Moines (DSM)?

via Atlanta ≈ 4h 19m, via Orlando ≈ 4h 22m, via Miami ≈ 4h 23m (estimated flying time, excluding layovers).

from 15,000 JAL miles, from 30,000 ANA miles (economy, one way, based on the published award charts).

Owen Roberts International Airport (GCM) to Des Moines International Airport (DSM)・2,733 km

No nonstop flights. The fastest connection is via Atlanta (ATL), about 4h 19m of flying time (layover not included).

With milesJAL 15,000 miles+ (via ORD)ANA 30,000 miles+ (via ORD)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

15 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.