Are there nonstop flights from Sioux Falls (FSD) to Indianapolis (IND)?

No. The fastest connection is via Chicago, about 2h 12m of total flying time.

What is the fastest connection from Sioux Falls (FSD) to Indianapolis (IND)?

via Chicago ≈ 2h 12m, via Minneapolis ≈ 2h 19m, via Nashville ≈ 2h 52m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Sioux Falls Regional Airport (FSD) to Indianapolis International Airport (IND)・968 km

No nonstop flights. The fastest connection is via Chicago (ORD), about 2h 12m of flying time (layover not included).

With milesANA 15,000 miles+ (via ORD)JAL 15,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

6 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.