Are there nonstop flights from Sioux Falls (FSD) to Wilmington (ILM)?

No. The fastest connection is via Chicago, about 3h 18m of total flying time.

What is the fastest connection from Sioux Falls (FSD) to Wilmington (ILM)?

via Chicago ≈ 3h 18m, via Nashville ≈ 3h 22m, via Minneapolis ≈ 3h 26m (estimated flying time, excluding layovers).

from 15,000 JAL miles (economy, one way, based on the published award charts).

Sioux Falls Regional Airport (FSD) to Wilmington International Airport (ILM)・1,924 km

No nonstop flights. The fastest connection is via Chicago (ORD), about 3h 18m of flying time (layover not included).

With milesJAL 15,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

7 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.