Are there nonstop flights from Frankfurt am Main (FRA) to Santo Domingo (SDQ)?

Yes. Condor Flugdienst fly this route. Flight time is about 9h 28m.

What is the fastest connection from Frankfurt am Main (FRA) to Santo Domingo (SDQ)?

via Puerto Plata ≈ 10h 6m, via Osbourn ≈ 10h 25m, via Madrid ≈ 10h 32m (estimated flying time, excluding layovers).

from 35,000 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Frankfurt Main Airport (FRA) to Las Américas International Airport (SDQ)・7,616 km

Nonstop flights available (1 airline). Flight time about 9h 28m. Nonstop return flights also operate.

With milesANA 35,000 miles+ (via EWR)JAL 37,000 miles+ (via MAD)Economy, one way, estimate. Tap a connection for miles by cabin.

18 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.