Are there nonstop flights from Frankfurt am Main (FRA) to Pisa (PSA)?

Yes. Air Dolomiti fly this route. Flight time is about 1h 21m.

What is the fastest connection from Frankfurt am Main (FRA) to Pisa (PSA)?

via Prague ≈ 2h 23m, via Brussels ≈ 2h 26m, via Zadar ≈ 2h 27m (estimated flying time, excluding layovers).

from 15,000 JAL miles (economy, one way, based on the published award charts).

Frankfurt Main Airport (FRA) to Pisa International Airport (PSA)・719 km

Nonstop flights available (1 airline). Flight time about 1h 21m. Nonstop return flights also operate.

With milesJAL 15,000 miles+ (via LHR)Economy, one way, estimate. Tap a connection for miles by cabin.

15 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.