Are there nonstop flights from Frankfurt am Main (FRA) to Medellín (MDE)?

No. The fastest connection is via Punta Cana, about 11h 41m of total flying time.

What is the fastest connection from Frankfurt am Main (FRA) to Medellín (MDE)?

via Punta Cana ≈ 11h 41m, via Santo Domingo ≈ 11h 44m, via Maiquetía ≈ 11h 44m (estimated flying time, excluding layovers).

from 35,000 ANA miles (economy, one way, based on the published award charts).

Frankfurt Main Airport (FRA) to Jose Maria Córdova International Airport (MDE)・9,053 km

No nonstop flights. The fastest connection is via Punta Cana (PUJ), about 11h 41m of flying time (layover not included).

With milesANA 35,000 miles+ (via BOG)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

16 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.