Are there nonstop flights from Firenze (FLR) to San Francisco (SFO)?

No. The fastest connection is via Zurich, about 12h 34m of total flying time.

What is the fastest connection from Firenze (FLR) to San Francisco (SFO)?

via Zurich ≈ 12h 34m, via London ≈ 12h 34m, via Paris ≈ 12h 35m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 45,000 JAL miles (economy, one way, based on the published award charts).

Florence Airport, Peretola (FLR) to San Francisco International Airport (SFO)・9,826 km

No nonstop flights. The fastest connection is via Zurich (ZRH), about 12h 34m of flying time (layover not included).

With milesANA 27,500 miles+ (via ZRH)JAL 45,000 miles+ (via LHR)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

12 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.