Are there nonstop flights from Rome (FCO) to Paphos (PFO)?

Yes. Ryanair fly this route. Flight time is about 2h 46m.

What is the fastest connection from Rome (FCO) to Paphos (PFO)?

via Rhodes ≈ 3h 16m, via Mykonos ≈ 3h 16m, via Naples ≈ 3h 16m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Rome–Fiumicino Leonardo da Vinci International Airport (FCO) to Paphos International Airport (PFO)・1,928 km

Nonstop flights available (1 airline). Flight time about 2h 46m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via ATH)JAL 15,000 miles+ (via AMM)Economy, one way, estimate. Tap a connection for miles by cabin.

35 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.