Are there nonstop flights from Rome (FCO) to Indianapolis (IND)?

No. The fastest connection is via Toronto, about 10h 10m of total flying time.

What is the fastest connection from Rome (FCO) to Indianapolis (IND)?

via Toronto ≈ 10h 10m, via Detroit ≈ 10h 10m, via Dublin ≈ 10h 14m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Rome–Fiumicino Leonardo da Vinci International Airport (FCO) to Indianapolis International Airport (IND)・7,792 km

No nonstop flights. The fastest connection is via Toronto (YYZ), about 10h 10m of flying time (layover not included).

With milesANA 27,500 miles+ (via IAD)JAL 37,000 miles+ (via PHL)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

20 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.