Are there nonstop flights from Rome (FCO) to Guatemala City (GUA)?

No. The fastest connection is via Miami, about 12h 44m of total flying time.

What is the fastest connection from Rome (FCO) to Guatemala City (GUA)?

via Miami ≈ 12h 44m, via Cancún ≈ 12h 46m, via Madrid ≈ 12h 49m (estimated flying time, excluding layovers).

from 35,000 ANA miles, from 45,000 JAL miles (economy, one way, based on the published award charts).

Rome–Fiumicino Leonardo da Vinci International Airport (FCO) to La Aurora International Airport (GUA)・9,955 km

No nonstop flights. The fastest connection is via Miami (MIA), about 12h 44m of flying time (layover not included).

With milesANA 35,000 miles+ (via EWR)JAL 45,000 miles+ (via MIA)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

14 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.