Are there nonstop flights from Newark (EWR) to Lyon (LYS)?

No. The fastest connection is via Paris, about 8h 21m of total flying time.

What is the fastest connection from Newark (EWR) to Lyon (LYS)?

via Paris ≈ 8h 21m, via Paris ≈ 8h 22m, via Dublin ≈ 8h 25m (estimated flying time, excluding layovers).

from 23,000 JAL miles, from 27,500 ANA miles (economy, one way, based on the published award charts).

Newark Liberty International Airport (EWR) to Lyon Saint-Exupéry Airport (LYS)・6,179 km

No nonstop flights. The fastest connection is via Paris (ORY), about 8h 21m of flying time (layover not included).

With milesJAL 23,000 miles+ (via CDG)ANA 27,500 miles+ (via GVA)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

41 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.