Are there nonstop flights from Ankara (ESB) to Bucharest (OTP)?

Yes. Pegasus Airlines, AJet fly this route. Flight time is about 1h 23m.

What is the fastest connection from Ankara (ESB) to Bucharest (OTP)?

via Istanbul ≈ 1h 57m, via Istanbul ≈ 1h 57m, via Antalya ≈ 2h 35m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Esenboğa International Airport (ESB) to Bucharest Henri Coandă International Airport (OTP)・751 km

Nonstop flights available (2 airlines). Flight time about 1h 23m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via IST)Economy, one way, estimate. Tap a connection for miles by cabin.

8 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.