Are there nonstop flights from Panama City Beach (ECP) to Manchester (MHT)?

No. The fastest connection is via Washington, about 3h 13m of total flying time.

What is the fastest connection from Panama City Beach (ECP) to Manchester (MHT)?

via Washington ≈ 3h 13m, via Charlotte ≈ 3h 14m, via Philadelphia ≈ 3h 14m (estimated flying time, excluding layovers).

from 15,000 JAL miles (economy, one way, based on the published award charts).

Northwest Florida Beaches International Airport (ECP) to Manchester-Boston Regional Airport (MHT)・1,891 km

No nonstop flights. The fastest connection is via Washington (DCA), about 3h 13m of flying time (layover not included).

With milesJAL 15,000 miles+ (via CLT)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

7 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.