Are there nonstop flights from Dushanbe (DYU) to Moscow (DME)?

Yes. Ural Airlines, Somon Air fly this route. Flight time is about 3h 59m.

What is the fastest connection from Dushanbe (DYU) to Moscow (DME)?

via Samarkand ≈ 4h 29m, via Samara ≈ 4h 32m, via Tashkent ≈ 4h 36m (estimated flying time, excluding layovers).

from 23,000 JAL miles (economy, one way, based on the published award charts).

Dushanbe International Airport (DYU) to Domodedovo International Airport (DME)・2,961 km

Nonstop flights available (2 airlines). Flight time about 3h 59m. Nonstop return flights also operate.

With milesJAL 23,000 miles+ (via OVB)Economy, one way, estimate. Tap a connection for miles by cabin.

23 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.