Are there nonstop flights from Detroit (DTW) to Lisbon (LIS)?

No. The fastest connection is via Toronto, about 8h 9m of total flying time.

What is the fastest connection from Detroit (DTW) to Lisbon (LIS)?

via Toronto ≈ 8h 9m, via Montréal ≈ 8h 10m, via Halifax ≈ 8h 10m (estimated flying time, excluding layovers).

from 23,000 JAL miles, from 27,500 ANA miles (economy, one way, based on the published award charts).

Detroit Metropolitan Wayne County Airport (DTW) to Lisbon Humberto Delgado Airport (LIS)・6,082 km

No nonstop flights. The fastest connection is via Toronto (YYZ), about 8h 9m of flying time (layover not included).

With milesJAL 23,000 miles+ (via PHL)ANA 27,500 miles+ (via EWR)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

25 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.